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Coxsackieviruses are members of the large family of enteroviruses. These are viruses that infect via chiefly the gastrointestinal tract (the so-called fecal-oral route of transmission), although also via the respiratory tract.
There are many viral types or strains identified by antibody testing (rarely bothered with) or viral cultures (even more rarely done). These different strains may cause all manner of different symptoms.
Some types of coxsackievirus are associated with specific clinical diseases:
Because these viruses spread chiefly by contact with fecal excretions, scrupulous handwashing is always the best defense against spread of these infections.